Description
Ask most people what melatonin does and they will tell you it helps you sleep. That is true, and it is the least interesting thing about the molecule.
Melatonin's sleep effect is receptor-mediated and saturates at 0.5–5 mg — which is why taking more does not help you sleep better. But melatonin is also a direct free-radical scavenger and a mitochondrial protector, and those effects are NOT receptor-mediated. They are concentration-dependent. Saturating tissue requires far more than saturating a receptor.
That is the entire argument for high-dose melatonin, and this book makes it properly.
INSIDE:
• Why 100 mg and 3 mg are two different drugs with the same name
• What the safety literature actually shows, including the 2022 Journal of Pineal Research meta-analysis on doses of 20–100 mg
• Melatonin and the mitochondria
• Melatonin during infection
• Melatonin and children — and why the high-dose data are absent there
• Delivery routes: why oral, suppository, and liposomal are not equivalent
• Who should not take it, and the sedation you must plan around
Dr. John Lieurance has spent years administering high-dose melatonin clinically. This is what he has learned — including the limits.
Melatonin is a dietary supplement. It is not a drug and is not intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before beginning any high-dose protocol.
Dr. John Lieurance, DC, ND is a chiropractic neurologist in Sarasota, Florida, with over 30 years in practice and 25+ in regenerative medicine.
ASIN: B09VDRSJBV
VSKU: BVV.B09VDRSJBV.G
Condition: Good
Author/Artist:Lieurance ND, DC, Dr John Andrew
Binding: Paperback
Note: Any images shown are stock photographs and product may differ from what is shown.
Condition Notes: The item shows wear from consistent use, but it remains in good condition and works perfectly. All pages and cover are intact including the dust cover, if applicable . Spine may show signs of wear. Pages may include limited notes and highlighting. May NOT include discs, access code or other supplemental materials.
ASIN: B09VDRSJBV
VSKU: BVV.B09VDRSJBV.G
Condition: Good
Author/Artist:Lieurance ND, DC, Dr John Andrew
Binding: Paperback
Note: Any images shown are stock photographs and product may differ from what is shown.
Condition Notes: The item shows wear from consistent use, but it remains in good condition and works perfectly. All pages and cover are intact including the dust cover, if applicable . Spine may show signs of wear. Pages may include limited notes and highlighting. May NOT include discs, access code or other supplemental materials.